TAB1 - C-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TAB1 - C-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in ad |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TAB1 |
| Other Names | [TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform alpha; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1] |
| Gene, Accession # | [TAB1], Gene ID: 10454, NCBI: NP_006107.1, UniProt: Q59FT7 |
| Catalog # | MBS3221618 |
| Price | $335 |
| Order / More Info | TAB1 - C-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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