PD-L1/CD274 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPD-L1/CD274
Clone[RBT-PDL1]
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formatunconjugated
Size5 Control Slides, 3 ml (Prediluted), 0.1 mL (Concentrate)
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Formalin/Paraffin
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DescriptionProgrammed death-ligand 1 (PD-L1) also known as CD274 or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene. Programmed death-ligand 1 (PD-L1) is a 40 kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other diseases.The upregulation of PD-L1 may allow cancers to evade the host immune system. An analysis of tumor specimens from patients with renal cell carcinoma found that high tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death. Ovarian cancer patients with higher expression of PD-L1 had a significantly po
ImmunogenImmunogen: Synthetic peptide corresponding to N-terminus residues of the human PD-L1 protein.
Other Namesn/a
Gene, Accession #[PD-L1/CD274]
Catalog #MBS370318
Price$130, $315, $345
Order / More InfoPD-L1/CD274 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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