HSF4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHSF4
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)
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DescriptionSpecificity: HSF4 antibody detects endogenous levels of total HSF4. Description: Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity.Function: DNA-binding protein that specifically binds heat shock promoter elements (HSE). Isoform HSF4A represses transcription while the isoform HSF4B activates transcription.Subunit Structure: Homotrimer. Exhibits constitutive DNA binding and forms trimers even in the absence of stress. Interacts with ALKBH4, DUSP26, MAPK1, MAPK2 and MAP kinase p38.Po
ImmunogenImmunogen: Purified recombinant fragment of human HSF4 expressed in E. Coli Subcellular Location: Nucleus Tissue Specificity: Expressed in heart, skeletal muscle, eye and brain, and at much lower levels in some other tissues.
Other Names[Cataract, Marner; CTM; Heat shock factor protein 4; Heat shock transcription factor 4; hHSF4; HSF 4; HSF4; HSF4_HUMAN; HSTF 4]
Gene, Accession #[HSF4], Gene ID: 3299, NCBI: NP_001035757.1, UniProt: Q9ULV5
Catalog #MBS9602413
Price$235, $295, $370
Order / More InfoHSF4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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