La Antigen Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | La Antigen |
| Clone | [4B10-E11-H11] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | 2.65mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Entrez Summary: The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly (U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein. UniPort Summary Function: Binds to the 3' poly (U) terminii of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitati |
| Immunogen | Immunogen: Purified recombinant human La Antigen protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of La Antigen and does not cross-react with related proteins. Sequence Similarities: Contains 1 HTH La-type RNA-binding domain. Contains 1 RRM (RNA recognition motif) domain. |
| Other Names | [Autoantigen La; La; La autoantigen; La autoantigen homolog; La protein; La ribonucleoprotein; La ribonucleoprotein domain family member 3; LA_HUMAN; LARP3; Lupus La antigen; Lupus La protein; Lupus La protein homolog; MGC118101; MGC93380; mRNA for autoantigen; OTTMUSP00000014043; RP23 273G23.1; Sjoegren syndrome type B antigen; Sjogren syndrome antigen B (autoantigen La); Sjogren syndrome antigen B; SS B; SS-B; SS-B/La protein; SSB], [LARP3; La/SSB] |
| Gene, Accession # | [La], Gene ID: 6741, NCBI: NP_001281074.1, UniProt: P05455 |
| Catalog # | MBS475587 |
| Price | $335 |
| Order / More Info | La Antigen Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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