SIGIRR Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SIGIRR |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SIGIRR Antibody: SIGIRR is a member of the Toll-like receptor-interleukin 1 receptor superfamily. Members of this family are defined by the presence of an intracellular Toll-IL-1R (TIR) domain. The Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. SIGIRR was originally identified through database analysis and was shown to have only one Ig domain as opposed to the normal three Ig folds seen in the TIR family. Similar to ST2, another TIR family member, it has been shown to negatively regulate IL-1 receptor and Toll-like receptor signaling. However, SIGIRR inhibits TLR-IL-1R signaling by dimerizing with |
| Immunogen | Immunogen: SIGIRR antibody was raised against a synthetic peptide corresponding to 15 amino acids at the C-terminus of human SIGIRR. Buffer: SIGIRR Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [SIGIRR; TIR8; Single Ig IL-1-related receptor; Single Ig IL-1R-related molecule; TIR8; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain], [SIGIRR; SIGIRR; TIR8; TIR8] |
| Gene, Accession # | [SIGIRR], Gene ID: 59307, NCBI: CAG33619, UniProt: Q6IA17 |
| Catalog # | MBS150698 |
| Price | $375 |
| Order / More Info | SIGIRR Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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