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Antigenic Specificity | Phospho- AKT1/PKBalpha (pSER473) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | Size: 100 ug/200 ul |
Applications | ELISA, Western Blot, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The motif corresponding to the major autophosphorylation site of the human AKT1 kinase protein. This antibody does not cross react to the non-phosphorylated AKT1 or with other unrelated phosphorylated serine. Ser473 corresponds to QFSYS in human, rat, mouse, chicken and canis of AKT/PKB proteins. Akt [also known as PKB (Protein kinase B) is a family of serine/threonine kinases that plays an important role in signal transduction. There are three known isoforms of Akt in mammalian cells [Akt1 (alpha), Akt2 (beta) and Akt3 (gamma)]; Akt is activated by insulin and growth and survival factors. Akt1 is phosphorylated within the activation loop at threonine 308 and the C-terminus at serine 473 (S473). Additionally, Akt has been referred to as an |
Immunogen | Antigen Preparation: A synthetic peptide containing the phosphorylated Ser473 motif of human AKT1. |
Other Names | n/a |
Gene, Accession # | [AKT1/PKBa (pS473)] |
Catalog # | MBS462005 |
Price | $265 |
Order / More Info | Phospho- AKT1/PKBalpha (pSER473) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |