IL-6 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | IL-6 |
| Clone | [AT1H6] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a, k |
| Format | Protein G purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1mg/ml |
| Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Interleukin-6, or IL-6, is a multifunctional protein, 212 amino acids in length that plays critical roles in host defense, immune response and hematopoiesis. IL-6 produced by T cells, macrophages, fibroblasts, endothelial and other cells. IL-6 induces proliferation or differentiation in many cell types including B cells, thymocytes and T cells. IL-6, in concert with TGF-Beta, is important for developing Th17 responses. The IL-6 receptor is a trimeric complex composed of an IL-6-specific a chain and a homodimer of the gp130 glycoprotein common to the IL-6, IL-11, CNTF, OSM and LIF receptors. Stimulation with IL-6 leads to gp130 homodimerization and the activation of associated kinases JAK1 and JAK2. Once activated, JAK1 and JAK2 phosphorylat |
| Immunogen | Immunogen: Recombinant IL-6 (30-212aa) purified from E. coli |
| Other Names | [Interleukin-6; Il-6], [IL6; IL6; CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2; IFNB2; IL-6; BSF-2; CDF; IFN-beta-2] |
| Gene, Accession # | [IL-6], Gene ID: 3569, NCBI: NP_000591, UniProt: P05231 |
| Catalog # | MBS200427 |
| Price | $240, $315 |
| Order / More Info | IL-6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Heinrich P.C., et al. (1998) Biochem J. 334: 297-314.; Heinrich P.C., et al. (1998) Z Ernahrungswiss. 37: 43-49.; Jones S.A. (2005) J Immunol. 175: 3463-3468. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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