Human Ubiquitin-like protein ISG15 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Ubiquitin-like protein ISG15
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatbiotin conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionUbiquitin-like protein that is conjugated to intracellular target proteins after IFN-alpha or IFN-beta stimulation. Its enzymatic pathway is partially distinct from that of ubiquitin, differing in substrate specificity and interaction with ligating enzymes. ISG15 conjugation pathway uses a dedicated E1 enzyme, but seems to converge with the Ub conjugation pathway at the level of a specific E2 enzyme. Targets include STAT1, SERPINA3G/SPI2A, JAK1, MAPK3/ERK1, PLCG1, EIF2AK2/PKR, MX1/MxA, and RIG-1. Deconjugated by USP18/UBP43. Shows specific chemotactic activity towards neutrophils and activates them to induce release of eosinophil chemotactic factors. May serve as a trans-acting binding factor directing the association of ligated target prot
ImmunogenImmunogen: Recombinant human Ubiquitin-like protein ISG15 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-50366 / sc-130791
Other Names[G1P2; UCRP; Interferon-induced 15 kDa protein Interferon-induced 17 kDa protein IP17 Ubiquitin cross-reactive protein hUCRP], [ISG15; ISG15; G1P2; IP17; UCRP; IFI15; IMD38; hUCRP; G1P2; UCRP; IP17; hUCRP]
Gene, Accession #[ISG15], Gene ID: 9636, NCBI: NP_005092.1, UniProt: P05161
Catalog #MBS715615
Price$160, $235
Order / More InfoHuman Ubiquitin-like protein ISG15 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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