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Antigenic Specificity | Bcl-G |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | ion exchange purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Although antibody should react with both isoforms, only the Bcl-GS protein has been observed. Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bcl-G. The mRNA of Bcl-G encodes 2 isoforms, Bcl-GL, which is widely expressed in multiple tissues, and Bcl-GS, which is only found in testis. The Bcl-GS protein is predominantly localized to cytoplasmic organelles whereas Bcl-GL was distributed throughout the cytosol. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a peptide corresponding to 15 amino acids near the C-terminus of human Bcl-G. |
Other Names | [Bcl-2-like 14] |
Gene, Accession # | [Bcl-G], Gene ID: 79370, NCBI: NP_110393.1 |
Catalog # | MBS9401701 |
Price | $320 |
Order / More Info | Bcl-G Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |