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Antigenic Specificity | Phosphoserine |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | General |
Isotype | n/a |
Format | APC-Cy7 conjugate |
Size | 0.4 mL |
Concentration | 0.25 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects proteins phosphorylated on serine residues. Does not cross-react with phosphotyrosine. Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine; others act on tyrosine, and a number (dual specificity kinases) act on all three. Because phosphorylation can occur at multiple sites on any given protein, it can therefore change the function or localization of that protein at |
Immunogen | Immunogen: Phosphoserine conjugated to KLH, and phosvitin mixture |
Other Names | [Rabbit Phosphoserine; Phospho-ser; pS; pSer; Phospho-serine] |
Gene, Accession # | n/a |
Catalog # | MBS8004211 |
Price | $525 |
Order / More Info | Phosphoserine Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Goto H. et al. (2005) Nature Cell Biology 8: 180-187. 2. Blume-Jensen P. and Hunter T. (2001) Nature 411: 355-365. 3. Downward J. (2001) Nature 411: 759-762. 4. Pawson T. and Saxton T.M. (1999) Cell 97: 675-678. 5. Ostrovsky P.C. (1995) Genes Dev. 9(16): 2034-2041. |