c-erbB-2/Her2 Antibody from MYBIOSOURCE INC.

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Antigenic Specificityc-erbB-2/Her2
Clone[ABM45F5]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b kappa
FormatProtein G purified
Size0.025 mg, 0.1 mg
Concentrationn/a
ApplicationsImmunohistochemistry (IHC)
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DescriptionHER2, a known proto-oncogene, is located at the long arm of human chromosome 17 (17q12), encoding a type 1 tyrosine kinase growth factor receptor and the role of HER2 in the development of numerous types of human cancer. HER2 is a transmembrane receptor comprising an extracellular domain (ECD), a single transmembrane domain, and an intracellular domain (ICD) with tyrosine-kinase activity. The high-expression and amplification of C-erbB-2 and its protein products (P185) are found in a wide variety of tumors. HER2 is overexpressed in 10% to 35% of gastric and gastroesophageal junction (GEJ) adenocarcinomas.
ImmunogenImmunogen Information: A partial length protein (amino acids 301-522) was used as the immunogen for this antibody (from extra cellular domain of c-erbB-2).
Other Names[ERBB2; HER2; MLN19; NEU; NGL; Metastatic lymph node gene 19 protein; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; to c-erbB-2/Her2; c-erbB-2/Her2; c-erbB-2/Her2], [ERBB2; ERBB2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; HER2; MLN19; NEU; NGL; MLN 19]
Gene, Accession #[ERBB2], Gene ID: 2064, NCBI: P04626.1, UniProt: P04626
Catalog #MBS668309
Price$145, $290
Order / More Infoc-erbB-2/Her2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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