Pin1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Pin1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Pin1 |
| Clone | [3G8] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, k |
| Format | Protein G purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1mg/ml |
| Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Human Pin 1 is a peptidyl-prolyl cis/trans isomerase (PPIase) that interacts with NIMA and essential for cell cycle regulation. Pin1 is nuclear PPIase containing a WW protein interaction domain, and is structurally and functionally related to Ess1/Ptf1, an essential protein in budding yeast. PPIase activity is necessary for Ess1/Pin1 function in yeast. Pin1 is thus an essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Substrates of Pin1 include the mitotic regulators (Cdc25 phosphatase and NIMA,PLk I, Wee, and Myt1 kinases), several transcription factors likebeta-Catenin, c-Jun, and the tumor suppressor protein p53, and some specific proteins like the RNA Pol II, the c |
| Immunogen | Immunogen: Recombinant human Pin1 (1-163aa) purified from E. coli |
| Other Names | [Protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; PIN1; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; EC 5.2.1.8; Rotamase Pin1; PPIase Pin1; DOD; uBL5; PIN1; PPIase; EC 5.2.1.8; Rotamase Pin1; PPIase Pin1; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1], [PIN1; PIN1; DOD; UBL5; PPIase Pin1] |
| Gene, Accession # | [Pin1], Gene ID: 5300, NCBI: NP_006212, UniProt: Q13526 |
| Catalog # | MBS200035 |
| Price | $240, $315 |
| Order / More Info | Pin1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Wulf GM, et al., (2002) J Biol. Chem. 277 (50)47976-47979; Hamdane M, et al., (2002) J Mol Neurosci. 19 (3) ; 275-287; Zheng H, et al., (2002) Nature 419 (6909) 853-857 Lu KP. et al., (1996) Nature 380 (6574) 544-547.; Campbell HD, et al., (1997) Genomics 44 (2), 157-162 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies