p70 S6 Kinase (Phospho-Thr389/412) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | p70 S6 Kinase (Phospho-Thr389/412) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous level of p70 S6 Kinase only when phosphorylated at tyrosine 389/tyrosine 412. Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.Hong S, et al. (2014) J Biol ChemPuustinen P, et al. (2014) CJ Cell Biol 204, 713-27 Martineau Y, et al. (2014) Mol Cell Biol 34, 1046-53 |
| Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of threonine389/412(G-F-T(p)-Y-V) derived from Human p70 S6 Kinase. Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Other Names | [KS6B1; P70-S6K; RPS6KB1; Ribosomal protein S6 kinase; polypeptide 1] |
| Gene, Accession # | Gene ID: 6198, NCBI: NP_001258971.1, UniProt: P23443 |
| Catalog # | MBS9403042 |
| Price | $200, $255 |
| Order / More Info | p70 S6 Kinase (Phospho-Thr389/412) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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