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Antigenic Specificity | BMP9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BMP9 antibody detects endogenous levels of total BMP9. Function: Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.Subunit Structure: Homodimer; disulfide-linked (PubMed:25237187, PubMed:28564608). Detected in extracellular fluid as mature homodimer, and in complex with its propeptide (PubMed:21710321, PubMed:25237187). Interacts with ACVRL1, BMPR2 and ACVR2B with high affinity (in vitro) (PubMed:22799562, PubMed:22347366, PubMed:25237187, PubMed:25751889). Identified in a complex with ACVRL1 and ACVR2B (PubMed:22718755). Has ten times lower affinity for ACVR2A (in vitro) |
Immunogen | Immunogen: A synthesized peptide derived from human BMP9 Subcellular Location: Secreted Tissue Specificity: Detected in blood plasma (at protein level). Predicted Cross Reactivity: Horse, Sheep, Rabbit Similarity: Horse (89%), Sheep (89%), Rabbit (100%) |
Other Names | [BMP 9; Bone morphogenetic protein 9; GDF 2; GDF2; growth differentiation factor 2; Growth/differentiation factor 2; HHT5] |
Gene, Accession # | [BMP9], Gene ID: 2658, NCBI: NP_057288.1, UniProt: Q9UK05 |
Catalog # | MBS9608335 |
Price | $240, $280 |
Order / More Info | BMP9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |