BMP9 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBMP9
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: BMP9 antibody detects endogenous levels of total BMP9. Function: Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.Subunit Structure: Homodimer; disulfide-linked (PubMed:25237187, PubMed:28564608). Detected in extracellular fluid as mature homodimer, and in complex with its propeptide (PubMed:21710321, PubMed:25237187). Interacts with ACVRL1, BMPR2 and ACVR2B with high affinity (in vitro) (PubMed:22799562, PubMed:22347366, PubMed:25237187, PubMed:25751889). Identified in a complex with ACVRL1 and ACVR2B (PubMed:22718755). Has ten times lower affinity for ACVR2A (in vitro)
ImmunogenImmunogen: A synthesized peptide derived from human BMP9 Subcellular Location: Secreted Tissue Specificity: Detected in blood plasma (at protein level). Predicted Cross Reactivity: Horse, Sheep, Rabbit Similarity: Horse (89%), Sheep (89%), Rabbit (100%)
Other Names[BMP 9; Bone morphogenetic protein 9; GDF 2; GDF2; growth differentiation factor 2; Growth/differentiation factor 2; HHT5]
Gene, Accession #[BMP9], Gene ID: 2658, NCBI: NP_057288.1, UniProt: Q9UK05
Catalog #MBS9608335
Price$240, $280
Order / More InfoBMP9 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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