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Antigenic Specificity | Ga15 / 16 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Galpha16 is the only heterotrimeric G protein with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of Galpha16. The G protein is known to couple a large number of G protein-coupled receptors to PLC-beta and can lead to production of the secondary messengers diacylglycerol and inositol phosphates. Targeted deletion of Galpha15, a mouse orthologue of human Galpha16, causes reduced C5alpha receptor signaling. Galpha16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 356of human G 15 |
Other Names | [G alpha binding protein], [GNA15; GNA15; GNA16; GNA16; G alpha-15; G-protein subunit alpha-15; G alpha-16; G-protein subunit alpha-16] |
Gene, Accession # | [Ga15/16], Gene ID: 2769, NCBI: AAC25612 |
Catalog # | MBS840543 |
Price | $150, $300 |
Order / More Info | Ga15 / 16 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |