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Antigenic Specificity | CD40L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: CD40, also known as bp50 or CDW40, is a type I membrane protein found on the surface of B cells and primary carcinomas. It belongs to the TNF-R family. CD40 serves as the receptor for CD40 ligand (CD40L), a cytokine expressed on the cell surface of T cells. CD40 plays a critical role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center thromugh interaction with T cells expressing CD40L, and activation of CD4+ T cells. Ligation of CD40 with its ligand preferentially induces stress-activated protein kinases in B lymphocytes. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 246 of human CD40 Ligand |
Other Names | [CD40LG; CD154; TRAP; gp39; # CD40L; IMD3; IGM; hCD40L; TNFSF5. HIGM1; CD40-L], [CD40LG; CD40LG; IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L; CD40L; TNFSF5; TRAP; CD40-L; TRAP] |
Gene, Accession # | [CD40L], Gene ID: 959, NCBI: NP_000065.1, UniProt: P29965 |
Catalog # | MBS840387 |
Price | $150, $330 |
Order / More Info | CD40L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |