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Antigenic Specificity | LAT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Linker for activation of T-cells family member 1(LAT) detection. Tested with WB, IHC-P, ICC in Human. Background: Linker for activation of T cells, also known as LAT, is a protein which in humans is encoded by the LAT gene. This gene is mapped to 16p11.2. The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor(TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located ne |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LAT (242-262aa QEAEEVEEEGAPDYENLQELN), different from the related mouse and rat sequences by six amino acids. |
Other Names | [Linker for activation of T-cells family member 1; linker for activation of T cells; 36 kDa phospho tyrosine adapter protein; 36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; LAT 1; lat; LAT_HUMAN; LAT1; Linker for activation of T cells; Linker for activation of T cells family member 1; linker for activation of T cells, transmembrane adaptor; Linker for activation of T-cells family member 1; p36 38; p36-38; pp36], [LAT; LAT; LAT1; pp36; pp36] |
Gene, Accession # | [LAT], Gene ID: 27040, NCBI: O43561.1, UniProt: O43561 |
Catalog # | MBS176785 |
Price | $315 |
Order / More Info | LAT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |