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Antigenic Specificity | MYO5B (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | humanpredicted: mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MYO5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 7-30 amino acids from MYO5B. May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis. |
Immunogen | n/a |
Other Names | [Purified Rabbit (Pab); Unconventional myosin-Vb; MYO5B; KIAA1119] |
Gene, Accession # | [MYO5B], Gene ID: 4645, NCBI: NP_001073936.1, UniProt: Q9ULV0 |
Catalog # | MBS9216766 |
Price | $165, $370 |
Order / More Info | MYO5B (N-Term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Hirosawa M.,et al.DNA Res. 6:329-336(1999).Ohara O.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.Ota T.,et al.Nat. Genet. 36:40-45(2004).Yamakawa H.,et al.Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.Nusbaum C.,et al.Nature 437:551-555(2005). |