Phospho-Histone H3 (S10) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Phospho-Histone H3 (S10) |
| Clone | [44AT1032.72] |
| Host Species | Mouse |
| Reactive Species | human, mouse (predicted reactivity: bovine, rat, chicken, zebrafish, Xenopus, C Elegans, Drosophila, porcine, rabbit, yeast) |
| Isotype | IgG1 |
| Format | purified |
| Size | 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Histone H3 Antibody is generated from mice immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S10 of human Histone H3. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replicati |
| Immunogen | n/a |
| Other Names | [Histone H33; H3F3A; H33A; H3F3] |
| Gene, Accession # | [H3F3A], Gene ID: 3020, NCBI: NP_002098.1, UniProt: P84243 |
| Catalog # | MBS9200028 |
| Price | $370 |
| Order / More Info | Phospho-Histone H3 (S10) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Distinct factors control histone variant H3.3 localization at specific genomic regions. Goldberg AD, et al. Cell, 2010 Mar 5. PMID 20211137. New functions for an old variant: no substitute for histone H3.3. Elsaesser SJ, et al. Curr Opin Genet Dev, 2010 Apr. PMID 20153629. ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells. Wong LH, et al. Genome Res, 2010 Mar. PMID 20110566. Phosphorylation of histone H3 by protein kinase C signaling plays a critical role in the regulation of the developmentally important TBX2 gene. Teng H, et al. J Biol Chem, 2009 Sep 25. PMID 19633291. Organismal differences in post-translational modifications in histones H3 and H4. Garcia BA, et al. J Biol Chem, 2007 Mar 9. PMID 17194708. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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