LSD1 (N-term), 108-142 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LSD1 (N-term), 108-142 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This LSD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-142 amino acids from the N-terminal region of human LSD1. LSD1 is a histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD1 contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. LSD1 demethylates both mono- and tri-methylted 'Lys-4' of histone H3. This protein |
| Immunogen | n/a |
| Other Names | [Lysine-specific histone demethylase 1A; 1---; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2; KDM1A; AOF2; KDM1; KIAA0601; LSD1] |
| Gene, Accession # | [KDM1A], Gene ID: 23028, NCBI: NP_001009999.1, UniProt: O60341 |
| Catalog # | MBS9211984 |
| Price | $165, $370 |
| Order / More Info | LSD1 (N-term), 108-142 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Forneris,F., et al. FEBS Lett. 579 (10), 2203-2207 (2005) Shi,Y., et al. Cell 119 (7), 941-953 (2004) Hakimi,M.A., et al. J. Biol. Chem. 278 (9), 7234-7239 (2003) Hakimi,M.A., et al. PNAS 99 (11), 7420-7425 (2002) Humphrey,G.W., et al. J. Biol. Chem. 276 (9), 6817-6824 (2001) Ota, T., et al., Nat. Genet. 36(1):40-45 (2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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