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Antigenic Specificity | ZMY11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ZMY11 protein. Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) By similarity. Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.Hateboer G., EMBO J. 14:3159-3169(1995).Deloukas P., Nature 429:375-381(2004).Matsuoka S., Science 316:1160-1166(2007). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human ZMY11. |
Other Names | [Zinc finger MYND domain-containing protein 11; Adenovirus 5 E1A-binding protein; BS69 protein; ZMYND11; BS69] |
Gene, Accession # | [ZMY11], Gene ID: 10771, NCBI: NP_001189393.1, UniProt: Q15326 |
Catalog # | MBS9405651 |
Price | $200, $255 |
Order / More Info | ZMY11 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |