ZMY11 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityZMY11
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total ZMY11 protein. Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) By similarity. Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.Hateboer G., EMBO J. 14:3159-3169(1995).Deloukas P., Nature 429:375-381(2004).Matsuoka S., Science 316:1160-1166(2007).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human ZMY11.
Other Names[Zinc finger MYND domain-containing protein 11; Adenovirus 5 E1A-binding protein; BS69 protein; ZMYND11; BS69]
Gene, Accession #[ZMY11], Gene ID: 10771, NCBI: NP_001189393.1, UniProt: Q15326
Catalog #MBS9405651
Price$200, $255
Order / More InfoZMY11 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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