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Antigenic Specificity | F8 |
Clone | [5E9B2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: F8: coagulation factor VIII, procoagulant component. This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essenti |
Immunogen | Immunogen: Purified recombinant fragment of F8 expressed in E Coli. |
Other Names | [AHF; F8B; F8C; HEMA; FVIII], [AHF; F8B; F8C; HEMA; FVIII] |
Gene, Accession # | [F8], Gene ID: 2157 |
Catalog # | MBS475862 |
Price | $335 |
Order / More Info | F8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |