GABA-B Receptor 2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | GABA-B Receptor 2 |
| Clone | [S81-2] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | PerCP conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | Immunohistochemistry (IHC), Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Detects ~105kDa. No cross-reactivity against GABA(B)R1 Scientific Background: GABA (gamma-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B) and GABA(C) receptor. The ionotropic GABA(A) and GABA(C) receptors are ligand-gated ion channels that produce fast inhibitory synaptic transmission. In contrast, the metabotropic GABA(B) receptor is coupled to G proteins that modulate slow inhibitory synaptic transmission (1). Functional GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 where GABA(B)R1 binds the ligand and GABA(B)R2 is the primary G protein contact site (2). Two isoforms of GABA(B)R1 have been cloned: GA |
| Immunogen | n/a |
| Other Names | [BcDNA:GH07312; CG6706; CT20836; D GABA[[B]]R2; D Gaba2; FLJ36928; G protein coupled receptor 51; G-protein coupled receptor 51; GAB B R2; GABA B R2; GABA B receptor 2; GABA B RECEPTOR; GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABA[[B]]R2; GABAB R2; GABABR], [Gabbr2; Gabbr2; Gpr51; Gpr51; GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABABR2; Gb2] |
| Gene, Accession # | Gene ID: 83633, NCBI: NP_113990.1, UniProt: O88871 |
| Catalog # | MBS800143 |
| Price | $435 |
| Order / More Info | GABA-B Receptor 2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Jones K.A,. et al. (2000) Neuropsychopharmacology 23: S41-9. 2. Duthey B. et al. (2002) J Biol Chem. 277: 3236-41. 3. Kaupmann K. et al. (1997) Nature 386: 239-46. |
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MYBIOSOURCE INC.
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