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Antigenic Specificity | Synaptobrevin 2 |
Clone | [3E5] |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG1, k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Synaptobrevin 2 (Vesicle-associated membrane, VAMP2), which is an 18 kDa integral membrane protein localized to the cytoplasmic surface of synaptic vesicle, consists of a proline-rich N-terminal region, a highly conserved hydrophilic domain, followed by a transmembrane anchor and a C-terminal tail. Synaptobrevin 2 is predominantly expressed in Langerhans islets and glomerular cells. The N-terminal domain of the protein forms a specific SNARE complex with the target membrane-associated t- or Q-SNAREs syntaxin 1 and SNAP-25. This antibody recognizes specifically synaptobrevin 2, but it also shows a low affinity to synaptobrevin 1. |
Immunogen | Immunogen: Recombinant human Synaptobrevin 2 (1-89aa) purified from E. coli |
Other Names | [vesicle-associated membrane protein 2; VAMP2; SYB2; Synaptobrevin 2; VAMP-2; Synaptobrevin-2; Vesicle-associated membrane protein 2; vesicle-associated membrane protein 2 FLJ11460; RATVAMPB; RATVAMPIR; SYB; VAMP 2; Vesicle associated membrane protein 2; Vesicle-associated membrane protein 2 (synaptobrevin 2).], [VAMP2; VAMP2; SYB2; VAMP-2; SYB2; VAMP-2] |
Gene, Accession # | Gene ID: 6844, NCBI: NP_055047, UniProt: P63027 |
Catalog # | MBS200052 |
Price | $240, $315 |
Order / More Info | Synaptobrevin 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Andres C et al., (1995) Proc Natl Acad Sci USA 92:5987-5991; Jacobsson G et al., (1998) European Journal of Neuroscience 16:301-316; Scales SJ. et al (2002) J Biol. Chem. 227 (31):28271-28279; Pennuto M et al., (2003) Mol Biol Cell. 14:4909-19 |