GRIN2B (C-Term) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | GRIN2B (C-Term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mousepredicted: mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This GRIN2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1300-1332 amino acids from human GRIN2B. NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity). |
| Immunogen | n/a |
| Other Names | [Purified Rabbit (Pab); Glutamate receptor ionotropic; NMDA 2B; GluN2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B; NMDAR2B; NR2B; N-methyl-D-aspartate receptor subunit 3; NR3; hNR3; GRIN2B; NMDAR2B] |
| Gene, Accession # | [GRIN2B], Gene ID: 2904, NCBI: NP_000825.2, UniProt: Q13224 |
| Catalog # | MBS9216637 |
| Price | $165, $370 |
| Order / More Info | GRIN2B (C-Term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Adams S.L.,et al.Biochim. Biophys. Acta 1260:105-108(1995). Hess S.D.,et al.J. Pharmacol. Exp. Ther. 278:808-816(1996). Mandich P.,et al.Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases. Mandich P.,et al.Genomics 22:216-218(1994). Schito A.M.,et al.Neurosci. Lett. 239:49-53(1997). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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