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Antigenic Specificity | Protein Phosphatase 4C (PPP4C) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels Protein Phosphatase 4C and does not cross-react with related proteins. UniPort Summary Function: Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB r |
Immunogen | Immunogen: Purified recombinant human Protein Phosphatase 4C protein fragments expressed in E Coli. Cellular Localization: Cytoplasm; Nucleus |
Other Names | [PP4; PPX; PP4C; PPH3; PPP4; Protein Phosphatase 4C], [PPP4C; PPP4C; PP4; PPX; PP-X; PP4C; PPH3; PPP4; PPP4; PPX; PP4C; Pp4; PP-X] |
Gene, Accession # | [PPP4C], Gene ID: 5531, NCBI: NP_001290432.1, UniProt: P60510 |
Catalog # | MBS857875 |
Price | $300 |
Order / More Info | Protein Phosphatase 4C (PPP4C) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |