CASP7 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-CASP7 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CASP7 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The Stat1 transcription factor is activated in response to a large number of ligands (1) and is essential for responsiveness to IFN-alpha and IFN-gamma (2, 3). Phosphorylation of Stat1 at Tyr701 induces Stat1 dimerization, nuclear translocation, and DNA binding (4). Stat1 protein exists as a pair of isoforms, Stat1alpha (91 kDa) and the splice variant Stat1beta (84 kDa). In most cells, both isoforms are activated by IFN-alpha, but only Stat1alpha is activated by IFN-gamma. The inappropriate activation of Stat1 occurs in many tumors (5). In addition to tyrosine phosphorylation, Stat1 is also phosphorylated at Ser727 through a p38 mitogen-activated protein kinase (MAPK)-dependent pathway in response to IFN-alpha and other cellular stresses (6 |
| Immunogen | Immunogen: Recombinant protein of human STAT1. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [STAT1; DKFZp686B04100; ISGF-3; STAT91], [STAT1; STAT1; CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91] |
| Gene, Accession # | [CASP7], Gene ID: 6772, NCBI: NP_009330.1, UniProt: P42224 |
| Catalog # | MBS858535 |
| Price | $290 |
| Order / More Info | CASP7 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Heim, M.H. (1999) J. Recept. Signal. Transduct. Res. 19, 75-120. 2. Durbin, J.E. et al. (1996) Cell 84, 443-450. 3. Meraz, M.A. et al. (1996) Cell 84, 431-442. 4. Ihle, J.N. et al. (1994) Trends Biochem. Sci. 19, 222-227. 5. Frank, D.A. (1999) Mol. Med. 5, 432-456. 6. Wen, Z. et al. (1995) Cell 82, 241-250. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies