Human Granzyme K Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human Granzyme K antibody, protein, ELISA kits.
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| Antigenic Specificity | Human Granzyme K |
| Clone | [GM-24C3] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), CELISA, ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: anti-human Granzyme K (GrK; granzyme-3; NK-tryptase-2). Background: Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes. |
| Immunogen | Immunogen: Immunogen: cDNA |
| Other Names | [granzyme K; granzyme K; NK-Tryp-2; granzyme 3; granzyme-3; tryptase II; fragmentin-3; NK-tryptase-2; granzyme K (serine protease, granzyme 3; tryptase II); granzyme K (granzyme 3; tryptase II); Fragmentin-3; Granzyme-3; NK-tryptase-2; NK-Tryp-2], [GZMK; GZMK; TRYP2; TRYP2; NK-Tryp-2] |
| Gene, Accession # | Gene ID: 3003, NCBI: NP_002095.1, UniProt: P49863 |
| Catalog # | MBS468012 |
| Price | $505 |
| Order / More Info | Human Granzyme K Antibody from MYBIOSOURCE INC. |
| Product Specific References | Bade B, Lohrmann J, ten Brinke A, Wolbink AM, Wolbink GJ, ten Berge IJM, Virchow JC Jr,Luttmann W and CE Hack (2005). Detection of soluble human granzyme K in vitro and in vivo.Eur. J. Immunol. (10): 2940-2948.Bade B, Boettcher HE, Lohrmann J, Hink-Schauer C, Bratke K, Jenne DE, Virchow JC Jr andW. Luttmann (2005). Differential expression of the granzymes A, K and M and perforin in humanperipheral blood lymphocytes. Int Immunol. (11): 1419-1428. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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