JAK2 (Non-phospho) (Paired1007/1008) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | JAK2 (Non-phospho) (Paired1007/1008) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | Size: 100 ug/200 ul |
| Applications | ELISA, Western Blot, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes JAK2 without phosphorylated sites of Tyr1007/1008. It does not cross-react with phosphospecific peptide. The Janus tyrosine kinase family is consists of four members, JAK1, JAK2, JAK3 and Tyk2. Upon the cytokine ligand binding to its the receptors, the dimerization of the receptors occurs followed by phosphorylation of the receptors. The phosphorylation of receptors recruites the tyrosine kinase physically associated to the dimerized receptors, and the phosphorylate the kinase, thus activates the signal transducer and activator of thranscription (STAT1, 3, 5) and the other signal proteins. |
| Immunogen | Antigen Preparation: A synthetic peptide surrounding to the epitope -EYYK- without any phosphorylation of JAK2 protein from human, mouse and rat origins |
| Other Names | [Rabbit JAK2 (Non-phospho) (Paired 1007/1008; Janus Kinase 2], [JAK2; JAK2; JTK10] |
| Gene, Accession # | [JAK2 (Paired Y1007/1008)], Gene ID: 3717, NCBI: NP_004963.1, UniProt: O60674 |
| Catalog # | MBS462065 |
| Price | $285 |
| Order / More Info | JAK2 (Non-phospho) (Paired1007/1008) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yogev,O., et al. SHP-2 regulates SOCS-1-mediated Janus kinase-2 ubiquitination/degradation downstream of the prolactin receptor. J. Biol. Chem. 278 (52), 52021-52031 (2003) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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