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Antigenic Specificity | RAB8A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RAB8A antibody detects endogenous levels of total RAB8A. Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenoge |
Immunogen | Immunogen: A synthesized peptide derived from human RAB8A Subcellular Location: Cytoskeleton; Endosome; Golgi Apparatus; Plasma Membrane Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (83%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%), Chicken (100%), Xenopus (92%) |
Other Names | [AA409338; MEL; Mel transforming oncogene (derived from cell line NK14) RAB8 homolog; Mel transforming oncogene (derived from cell line NK14); Mel transforming oncogene (RAB8 homolog); Mel transforming oncogene; MGC124948; Oncogene c mel; Oncogene c-mel; RAB8; RAB8A; RAB8A member RAS oncogene family; RAB8A_HUMAN; Ras associated protein RAB8; Ras related protein Rab 8A; Ras-related protein Rab-8A] |
Gene, Accession # | [RAB8A], Gene ID: 4218, NCBI: NP_005361.2, UniProt: P61006 |
Catalog # | MBS9610152 |
Price | $240, $280 |
Order / More Info | RAB8A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |