NGF-Receptor (p75) /CD271 (Soft Tissue Tumor Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNGF-Receptor (p75) /CD271 (Soft Tissue Tumor Marker)
Clone[NGFR5]
Host SpeciesMouse
Reactive Specieshuman, monkey, baboon, cat, rabbit, ferret. does not react with mouse and rat
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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DescriptionSpecificity: It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and lo
ImmunogenImmunogen: NGFR from A875 melanoma cells
Other Names[CD271; Gp80-LNGFR; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Nerve growth factor receptor (NGFR); TNFR superfamily member 16; p75 ICD; p75 Neurotrophin receptor; Tumor necrosis factor receptor superfamily member 16 (TNFRSF16)], [NGFR; NGFR; CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; TNFRSF16; NGF receptor]
Gene, Accession #[NGFR], Gene ID: 4804, NCBI: NP_002498.1, UniProt: P08138
Catalog #MBS439529
Price$190, $340, $340
Order / More InfoNGF-Receptor (p75) /CD271 (Soft Tissue Tumor Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMarano N, et. al. Journal of Neurochemistry, 1987, 48:225-32
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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