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Antigenic Specificity | NGF-Receptor (p75) /CD271 (Soft Tissue Tumor Marker) |
Clone | [NGFR5] |
Host Species | Mouse |
Reactive Species | human, monkey, baboon, cat, rabbit, ferret. does not react with mouse and rat |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and lo |
Immunogen | Immunogen: NGFR from A875 melanoma cells |
Other Names | [CD271; Gp80-LNGFR; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Nerve growth factor receptor (NGFR); TNFR superfamily member 16; p75 ICD; p75 Neurotrophin receptor; Tumor necrosis factor receptor superfamily member 16 (TNFRSF16)], [NGFR; NGFR; CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; TNFRSF16; NGF receptor] |
Gene, Accession # | [NGFR], Gene ID: 4804, NCBI: NP_002498.1, UniProt: P08138 |
Catalog # | MBS439529 |
Price | $190, $340, $340 |
Order / More Info | NGF-Receptor (p75) /CD271 (Soft Tissue Tumor Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Marano N, et. al. Journal of Neurochemistry, 1987, 48:225-32 |