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Antigenic Specificity | VAC14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.6 mg/mL |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total VAC14 protein. This gene encodes a scaffold protein that is a component of the PIKfyve protein kinase complex. This complex is responsible for the synthesis of phosphatidylinositol 3,5-bisphosphate, an important component of cellular membranes, from phosphatidylinositol 3-phosphate. Mice lacking a functional copy of this gene exhibit severe neurodegeneration. Mutations in the human gene have been identified in patients with a childhood onset progressive neurological disorder characterized by impaired movement, dystonia, and striatal abnormalities. |
Immunogen | Immunogen: Fusion protein of human VAC14 Immunogen Type: Peptide |
Other Names | [TRX; TAX1BP2; ArPIKfyve] |
Gene, Accession # | [VAC14], Gene ID: 55697, NCBI: NP_060522.3, UniProt: Q08AM6 |
Catalog # | MBS9430730 |
Price | $255 |
Order / More Info | VAC14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |