TNF-RI, Mouse Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TNF-RI, Mouse |
| Clone | 55R-170 |
| Host Species | Armenian hamster |
| Reactive Species | mouse |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), FS, Immunoassay (IA), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody 55R-170 recognizes the extracellular part of mouse Tumor Necrosis Factor Receptor superfamily member 1A (TNF-RI), also known as CD120a or p55. TNF-RI belongs to the large TNF receptor family, among which TNF-RII (TNF-R p75-80), lymphotoxin-beta receptor (LTbetaR) and the Herpes virus entry mediator (HVEM). Ligands for these receptors belong to the Tumor Necrosis Factor (TNF) superfamily of cytokines, which activate signaling pathways for cell survival, death, and differentiation that orchestrate the development, organization and homeostasis of lymphoid, mammary, neuronal and ectodermal tissues. TNF-RI contains a characteristic structural cassette termed death domain in its sequence that is conser |
| Immunogen | Immunogen: Purified soluble extracellular domain of mouse TNF-RI |
| Other Names | [TNFR type I, CD120a, TNF-RI, TNF-R55, TNFRp55, p55-R, TNF receptor alpha chain], [TNFRSF1A; TNFRSF1A; TNFR1; TNF-R1; TNF-RI; TNFR-I] |
| Gene, Accession # | [TNF-RI], Gene ID: 282527, NCBI: AAB65143.1 |
| Catalog # | MBS584105 |
| Price | $520 |
| Order / More Info | TNF-RI, Mouse Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Sheehan, K et al; Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75. J Exp Med 1995, 181: 607 2. Pinckard, J et al; Ligand-induced formation of p55 and p75 tumor necrosis factor receptor heterocomplexes on intact cells. J Biol Chem 1997, 272: 10784 3. Ji, H et al; Critical roles for interleuking 1 and tumor necrosis factor alpha in antibody-induced arthritis. J Exp Med 2002, 196: 77 4. Lee, S et al; Inhibition of TCR-induced CD8 T cell death by IL-12: regulation of Fas ligand and cellular FLIP expression and caspase activation by IL-12. J Immunol 2003, 170: 2456 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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