NEU4 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NEU4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: NEU4 antibody detects endogenous levels of NEU4. Function: May function in lysosomal catabolism of sialylated glycoconjugates. Has sialidase activity towards synthetic substrates, such as 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid (4-MU-NANA or 4MU-NeuAc). Has a broad substrate specificity being active on glycoproteins, oligosaccharides and sialylated glycolipids.Post-translational Modifications: According to PubMed:15213228, phosphorylation of mannose residues may ensure efficient transport of isoform 2 to the lysosomes via the mannose 6-phosphate receptor. Isoform 2 is glycosylated.Similarity: Belongs to the glycosyl hydrolase 33 family. |
| Immunogen | Immunogen: A synthesized peptide derived from human NEU4. Subcellular Location: Isoform 1: Membrane; Peripheral Membrane Protein. Isoform 2: Lysosome Lumen. Tissue Specificity: Ubiquitous with higher expression in heart, skeletal muscle, liver and placenta. |
| Other Names | [N acetyl alpha neuraminidase 4; Neuraminidase 4; Sialidase 4] |
| Gene, Accession # | [NEU4], Gene ID: 129807, NCBI: NP_001161071.1, UniProt: Q8WWR8 |
| Catalog # | MBS9603351 |
| Price | $240, $280 |
| Order / More Info | NEU4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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