p53 (S376) Antibody from MYBIOSOURCE INC.

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Antigenic Specificityp53 (S376)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein A purified
Size0.05 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 349-385 amino acids from human. Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the funct
Immunogenn/a
Other Names[Purified Rabbit (Pab); Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53; TP53; P53]
Gene, Accession #[p53], Gene ID: 7157, NCBI: NP_000537.3, UniProt: P04637
Catalog #MBS9231235
Price$165, $370
Order / More Infop53 (S376) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesZakut-Houri R.,et al.EMBO J. 4:1251-1255(1985). Lamb P.,et al.Mol. Cell. Biol. 6:1379-1385(1986). Harlow E.,et al.Mol. Cell. Biol. 5:1601-1610(1985). Harris N.,et al.Mol. Cell. Biol. 6:4650-4656(1986). Buchman V.L.,et al.Gene 70:245-252(1988).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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