Phospho-Mouse CASP3 (S12) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-Mouse CASP3 (S12)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.3
ApplicationsDot Blot (DB), ELISA (EIA)
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DescriptionThis mouse CASP3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S12 of mouse CASP3. This gene encodes a protein which is a member of thecysteine-aspartic acid protease (caspase) family. Sequentialactivation of caspases plays a central role in the execution-phaseof cell apoptosis. Caspases exist as inactive proenzymes whichundergo proteolytic processing at conserved aspartic residues toproduce two subunits, large and small, that dimerize to form theactive enzyme. This protein cleaves and activates caspases 6, 7 and9, and the protein itself is processed by caspases 8, 9 and 10. Itis the predominant caspase involved in
Immunogenn/a
Other Names[Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; LICE; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12; Casp3; Cpp32]
Gene, Accession #[Casp3], Gene ID: 12367, NCBI: NP_033940.1, UniProt: P70677
Catalog #MBS9213708
Price$165, $370
Order / More InfoPhospho-Mouse CASP3 (S12) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSrikanth, C.V., et al. Science 330(6002):390-393(2010) Li, F., et al. Cell Stem Cell 7(4):508-520(2010) Wang, L., et al. J. Neurosci. 30(39):13201-13210(2010) Gascon, E., et al. J. Neurosci. 30(37):12414-12423(2010) Bohsali, A., et al. BMC Microbiol. 10, 237 (2010) :
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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