ICOS (C-term), 156-185 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ICOS (C-term), 156-185 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry-Paraffin (IHC-P) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This ICOS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the C-terminal region of human ICOS. ICOS belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. |
| Immunogen | Function: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up- regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up- regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre- act |
| Other Names | [Inducible T-cell costimulator; Activation-inducible lymphocyte immunomediatory molecule; CD278; ICOS; AILIM] |
| Gene, Accession # | [ICOS], Gene ID: 29851, NCBI: NP_036224.1, UniProt: Q9Y6W8 |
| Catalog # | MBS9203882 |
| Price | $165, $370 |
| Order / More Info | ICOS (C-term), 156-185 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Okamoto, N., et al., Biochem. Biophys. Res. Commun. 310(3):691-702 (2003). Okamoto, T., et al., J. Rheumatol. 30(6):1157-1163 (2003). Riley, J.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(18):11790-11795 (2002). Haimila, K.E., et al., Immunogenetics 53(12):1028-1032 (2002). Witsch, E.J., et al., Eur. J. Immunol. 32(9):2680-2686 (2002). |
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