ACO1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ACO1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.1 mL |
| Concentration | 1.4 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total ACO1 protein. Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes. |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human aconitase 1, soluble |
| Other Names | [IRP1; ACONS; IREB1; IREBP; IREBP1] |
| Gene, Accession # | [ACO1], Gene ID: 48, NCBI: NP_001265281.1, UniProt: P21399 |
| Catalog # | MBS9401532 |
| Price | $255 |
| Order / More Info | ACO1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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