Chk1 (pSer280) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityChk1 (pSer280)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.05 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionRabbit anti Chk1 (pSer280) antibody recognizes Chk1 also known as checkpoint kinase-1, CHK1 checkpoint homolog or cell cycle checkpoint kinase, when phosphorylated at serine 280. Chk1 is a serine/threonine protein kinase that plays a crucial role in cell cycle control. Chk1 is involved in triggering cell cycle arrest, DNA repair and apoptosis (Bartek and Lukas 2003). Chk1 plays a critical role in preventing aberrant cells from progressing through the cell cycle (Thompson and Eastman 2013). Chk1 is phosphorylated at serine 280 by p90 RSK (Li et al. 2012) resulting in nuclear accumulation of Chk1.
ImmunogenImmunogen: Phospho specific-peptide corresponding to residues surrounding serine 280 of human Chk1
Other Names[Chk1 (pSer280)], [CHEK1; CHEK1; CHK1; CHK1]
Gene, Accession #[CHEK1], Gene ID: 1111, NCBI: O14757.2, UniProt: O14757
Catalog #MBS225212
Price$375
Order / More InfoChk1 (pSer280) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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