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Antigenic Specificity | Chk1 (pSer280) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Chk1 (pSer280) antibody recognizes Chk1 also known as checkpoint kinase-1, CHK1 checkpoint homolog or cell cycle checkpoint kinase, when phosphorylated at serine 280. Chk1 is a serine/threonine protein kinase that plays a crucial role in cell cycle control. Chk1 is involved in triggering cell cycle arrest, DNA repair and apoptosis (Bartek and Lukas 2003). Chk1 plays a critical role in preventing aberrant cells from progressing through the cell cycle (Thompson and Eastman 2013). Chk1 is phosphorylated at serine 280 by p90 RSK (Li et al. 2012) resulting in nuclear accumulation of Chk1. |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding serine 280 of human Chk1 |
Other Names | [Chk1 (pSer280)], [CHEK1; CHEK1; CHK1; CHK1] |
Gene, Accession # | [CHEK1], Gene ID: 1111, NCBI: O14757.2, UniProt: O14757 |
Catalog # | MBS225212 |
Price | $375 |
Order / More Info | Chk1 (pSer280) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |