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Antigenic Specificity | sRANK Ligand |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | sRANK Ligand Antibody: The receptor activator of NF-κB ligand (RANK-L) is a recently discovered member of the TNF-ligand family involved in the regulation of the T cell-dependent immune response, lymph node organogenesis and bone formation. RANK-L exists as both a normal, transmembrane form and a truncated, soluble form (sRANK-L), both of which can stimulate the receptor. Activation of T cells, such as by treatment with interleukin-7, induces RANK-L production and leads to an increase of osteoclast formation and bone loss. Finally, sRANK-L can activate the antiapoptotic kinase Akt through a signaling complex involving Src kinase and TRAF6, suggesting sRANK-L may also play a role in regulating apoptosis. This antibody will recognize bot |
Immunogen | Immunogen: sRANK-L antibody was raised against a 14 amino acid synthetic peptide from near the center of human sRANK-L. Buffer: sRANK Ligand Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [sRANK Ligand; ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TRANCE; hRANKL2; Tumor necrosis factor ligand superfamily member 11; Osteoclast differentiation factor; ODF; tumor necrosis factor (ligand) superfamily, member 11], [TNFSF11; TNFSF11; ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TRANCE; hRANKL2; OPGL; RANKL; TRANCE; ODF; OPGL; RANKL; TRANCE] |
Gene, Accession # | [TNFSF11], Gene ID: 8600, NCBI: NP_003692, UniProt: O14788 |
Catalog # | MBS150390 |
Price | $375 |
Order / More Info | sRANK Ligand Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |