Human CIDE-3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CIDE-3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunoblot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CIDE-3 [Human CIDE-3]. This antibody recognizes human CIDE-3. Sequence homology to the mouse CIDE-3 homolog, FSP27, is 93%. DNA fragmentation, induced by DNA fragmentation factor (DFF), is one of the critical steps in apoptosis. DFF is composed of two subunits, a 40-kDa caspase-activated nuclease (DFF40) and a 45-kDa inhibitor (DFF45). Recently a novel family of cell death-inducing DFF45-like effectors (CIDEs) has been identified. Human CIDE-3 is a novel CIDE. Two transcripts, CIDE-3 and CIDE-3alpha, are present in HepG2 and A375 cells. Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumors, CIDE-3 may play an important role in prevention of tumorigenes |
| Immunogen | Immunogen: Synthetic peptide corresponding to amino acids 10-25 (LLYPKSLSRHVSVRTS) of human CIDE-3 conjugated to KLH at the C-terminus. |
| Other Names | [CIDE-3; CIDE-3], [CIDEC; CIDEC; FSP27; CIDE-3; FLJ20871; FSP27] |
| Gene, Accession # | Gene ID: 63924, NCBI: NP_001186481.1, UniProt: Q96AQ7 |
| Catalog # | MBS194098 |
| Price | $335 |
| Order / More Info | Human CIDE-3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Liang, L et al. (2003) Biochem J 370: 195-203. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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