11beta-HSD1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-11beta-HSD1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | 11beta-HSD1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.03 mL, 0.1 mL, 0.2 mL |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: 11beta-HSD1 Polyclonal Antibody detects endogenous levels of 11beta-HSD1 protein. Hydroxysteroid 11-beta dehydrogenase 1 encoded by HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in HSD11B1 has been associated with obesity and insulin resistance in children. Mutations in HSD11B1 and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the |
| Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human 11beta-HSD1 at AA range: 10-90 |
| Other Names | [Rabbit 11beta-HSD1; HSD11B1; HSD11; HSD11L; Corticosteroid 11-beta-dehydrogenase isozyme 1; 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11-beta-HSD1] |
| Gene, Accession # | [11beta-HSD1], Gene ID: 3290, NCBI: NP_001193670.1, UniProt: P28845 |
| Catalog # | MBS9701278 |
| Price | $130, $220, $325 |
| Order / More Info | 11beta-HSD1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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