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Antigenic Specificity | ESR1 isoform1 (N-term), 130-157 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: porcine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ESR1 isoform1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-157 amino acids from the N-terminal region of human ESR1 isoform1. This gene encodes an estrogen receptor, a ligand-activatedtranscription factor composed of several domains important forhormone binding, DNA binding, and activation of transcription. Theprotein localizes to the nucleus where it may form a homodimer or aheterodimer with estrogen receptor 2. Estrogen and its receptorsare essential for sexual development and reproductive function, butalso play a role in other tissues such as bone. Estrogen receptorsare also involved in pathological processes including breastcancer, endometrial cance |
Immunogen | n/a |
Other Names | [Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1; ESR1; ESR; NR3A1] |
Gene, Accession # | [ESR1], Gene ID: 2099, NCBI: NP_000116.2, UniProt: P03372 |
Catalog # | MBS9213885 |
Price | $165, $370 |
Order / More Info | ESR1 isoform1 (N-term), 130-157 Antibody from MYBIOSOURCE INC. |
Product Specific References | Geradts, J., et al. Cancer Invest. 28(9):969-977(2010) Hayes, D.F., et al. Clin. Pharmacol. Ther. 88(5):626-629(2010) Lupien, M., et al. Genes Dev. 24(19):2219-2227(2010) Corbo, R.M., et al. J. Gerontol. A Biol. Sci. Med. Sci. (2010) In press : Kim, S., et al. Fertil. Steril. (2010) In press : |