DNMT3L Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-DNMT3L antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | DNMT3L |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Chromatin Immunoprecipitation (CHIP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting, and development (1, 2). Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2, and DNMT3 (1, 2). DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication. DNMT3A and DNMT3B are strongly expressed in embryonic stem cells with reduced expression in adult somatic tissues. DNMT3A and DNMT3B function as de novo methyltransferases that methylate previously unmethylated regions of DNA. DNMT2 is expressed at l |
| Immunogen | Immunogen: Recombinant protein of human DNMT3L Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [MGC1090; DNMT3L] |
| Gene, Accession # | [DNMT3L], Gene ID: 29947, NCBI: NP_037501.2, UniProt: Q9UJW3 |
| Catalog # | MBS8502325 |
| Price | $310 |
| Order / More Info | DNMT3L Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Hermann, A. et al. (2004) Cell Mol Life Sci 61, 2571-87. 2. Turek-Plewa, J. and Jagodzi?ski, P.P. (2005) Cell Mol Biol Lett 10, 631-47. 3. Jia, D. et al. (2007) Nature 449, 248-51. 4. Holz-Schietinger, C. and Reich, N.O. (2010) J Biol Chem 285, 29091-100. 5. Suetake, I. et al. (2004) J Biol Chem 279, 27816-23. 6. Ooi, S.K. et al. (2007) Nature 448, 714-7. 7. Otani, J. et al. (2009) EMBO Rep 10, 1235-41. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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