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Antigenic Specificity | CD74 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF. |
Immunogen | Immunogen: A synthesized peptide derived from human CD74. Subcellular Localization: Cell membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane. Golgi apparatus, trans-Golgi network. Endosome. Lysosome. Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane. |
Other Names | [HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33; CD74; CD74; DHLAG], [CD74; CD74; II; DHLAG; HLADG; Ia-GAMMA; DHLAG; Ii] |
Gene, Accession # | [CD74], Gene ID: 972, NCBI: NP_001020329.1, UniProt: P04233 |
Catalog # | MBS179633 |
Price | $160, $340, $340 |
Order / More Info | CD74 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |