Edit |   |
---|---|
Antigenic Specificity | Androgen Receptor |
Clone | [2H8] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype. |
Immunogen | Immunogen: Purified recombinant fragment of human AR expressed in E. Coli. |
Other Names | [NR3C4; KD; AIS; SMAX1; HUMARA] |
Gene, Accession # | [AR], Gene ID: 367, NCBI: NP_000035.2, UniProt: P10275 |
Catalog # | MBS8538592 |
Price | $280 |
Order / More Info | Androgen Receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |