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Antigenic Specificity | Phospho-TrkB (Y817) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The family of Trk receptor tyrosine kinases consists of TrkA, TrkB and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. TrkA regulates proliferation and is important for development and maturation of the nervous system. Point mutations, deletions and chromosomal rearrangements (chimeras) cause ligand-independent receptor dimerization and activation of TrkA. |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-TrkB (Y817) |
Other Names | [NTRK2; gp145-TrkB; Trk-B; TRKB; Tropomyosin-related kinase B; TrkB tyrosine kinase; Tyrosine kinase receptor B] |
Gene, Accession # | [TrkB], Gene ID: 4915, NCBI: NP_001007098.1, UniProt: Q16620 |
Catalog # | MBS8542618 |
Price | $280 |
Order / More Info | Phospho-TrkB (Y817) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |