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Antigenic Specificity | SHC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SHC Antibody detects endogenous levels of total SHC. Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. |
Immunogen | Immunogen: A synthesized peptide derived from human SHC |
Other Names | [SH2 domain protein C1; SHC; SHC-transforming protein 1; SHCA; Src homology 2 domain-containing-transforming protein C1] |
Gene, Accession # | [SHC], Gene ID: 6464, NCBI: NP_001123512.1, UniProt: P29353 |
Catalog # | MBS4751195 |
Price | $335 |
Order / More Info | SHC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |