CD25 / IL2RA (Activated Lymphocyte Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD25 / IL2RA (Activated Lymphocyte Marker) |
| Clone | [IL2RA/423] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG2a, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Functional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a protein of 55kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin's disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block I |
| Immunogen | Immunogen: Recombinant human IL2RA protein |
| Other Names | [IL2 Receptor alpha; IL2R alpha chain; IL2R; IL2R subunit alpha IL2RA; Interleukin-2 receptor subunit alpha; Ly43; p55; p55 chain; T Cell Growth Factor Receptor; TAC antigen; TCGFR], [IL2RA; IL2RA; p55; CD25; IL2R; IMD41; TCGFR; IDDM10; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA] |
| Gene, Accession # | [IL2RA], Gene ID: 3559, NCBI: NP_000408.1, UniProt: P01589 |
| Catalog # | MBS438597 |
| Price | $190, $340, $340 |
| Order / More Info | CD25 / IL2RA (Activated Lymphocyte Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | L.A. Rubin, et al, (1985) Hybidoma 4: 91-102. B. Boutin, et al, (1989) Neuropediatrics 20: 202-206. T.A. Waldmann, et al, (1989) Annu Rev Biochem 58: 875-911. T.A. Waldmann, et al, (1995) Blood 86: 4063-4075. Leukocyte Typing IV (W. Knapp, et al, eds.) Oxford University Press, Oxford, (1989) p. 403-40 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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