CDCA7L Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CDCA7L |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CDCA7L antibody detects endogenous levels of total CDCA7L. Function: Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.Subunit Structure: Interacts with MYC and PSIP1. |
| Immunogen | Immunogen: A synthesized peptide derived from human CDCA7L Subcellular Location: Cytoplasm. Nucleus. Note: associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction. Tissue Specificity: Ubiquitous. Overexpressed in medulloblastoma. |
| Other Names | [c Myc Interacting protein JPO2; CDCA7L; DKFZp762L0311; HR1; JPO2; Protein JPO2; R1; RAM2; Transcription Factor RAM2] |
| Gene, Accession # | [CDCA7L], Gene ID: 55536, NCBI: NP_001120842.1, UniProt: Q96GN5 |
| Catalog # | MBS9609233 |
| Price | $240, $280 |
| Order / More Info | CDCA7L Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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